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Prescribing Information

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Metalyse® 25 mg (TENECTEPLASE) is available for the thrombolytic treatment of acute ischaemic stroke (AIS) within 4.5 hours from last known well and after exclusion of intracranial haemorrhage1

Because Every 
Minute Matters

HRCT
  • Metalyse 25 mg for AIS
  • ThiNK Stroke
  • Clinical Trial Data
  • Dosing & Administration
  • Contraindications
  • Time is Brain
  • Resources

Welcome to the Resource Hub

Your central destination for practical tools, guidance, and educational materials to support the assessment and management of acute ischaemic stroke.

Designed for busy stroke clinicians, this collection brings together resources to help streamline decision‑making, enhance pathway delivery, and optimise patient care.

Learn more
Real‑World Guidance from Clinicians

Real‑World Guidance from Clinicians

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Learn more
How to reconstitute Metalyse 25 mg

How to reconstitute Metalyse 25 mg

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Learn more
Clinical Tools, Training & Support

Clinical Tools, Training & Support

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Reference

  1. Metalyse 25 mg (tenecteplase) Summary of Product Characteristics.

PC-GB-112287 April 2026

Reporting adverse events

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Boehringer Ingelheim Drug Safety on 0800 328 1627 (freephone).

Please be aware that this website contains promotional information about Boehringer Ingelheim medicines and services. Some of this may not be directly relevant to your scope of practice and it is your own decision whether you choose to view this information.

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